ABSTRACT
<p><b>OBJECTIVE</b>To assess the clinical efficacy on adhesive ileus treated by electroacupuncture (EA) at Zhigou (TE 6) and Zusanli (ST 36), and to explore the different effects of acupoint and non-acupoint.</p><p><b>METHODS</b>Forty cases were randomized into an acupoint group and a non-acupoint group, 20 cases in each one. At the same time of the basic treatment, in the acupoint group, EA was applied at bilateral Zhigou (TE 6) and Zusanli (ST 36). In the non-acupoint group, EA was applied at the sites (that were neither on any meridian nor belonged to any acupoint) that were 0.5 to 1 cm lateral to Zhigou (TE 6) and Zusanli (ST 36) on both sides. Acupuncture was given twice a day, lasting for 4 days totally. The situation of abdominal pain, the time for the improvement in abdominal distention, the time of first voluntary defecation, the time of solid food intake and the others were observed.</p><p><b>RESULTS</b>In the acupoint group, the abdominal pain and distention were relieved rapidly as compared with those in the non-acupoint group. The results of the assessment face scale (AFS), the first anal exhaust time [(51.35 +/- 32.40) h vs (101.85 +/- 53.87) h], the first defecation time [(82.70 +/- 57.27) h vs (154.70 +/- 145.28) h] and the first solid food intake time [(119.65 +/- 56. 16) h vs (231.95 +/- 180.89) h] were all remarkably improved as compared with those in the non-acupoint group, presenting the statistical significance (P<0.05, P<0.01). Concerning the case number for the conversion to surgery, the death number and the number for the re-admission in 1 year follow-up visit, there was no significant difference in statistics between two groups (all P>0.05). But, the data suggested that the results were improved in tendency in the acupoint group.</p><p><b>CONCLUSION</b>EA at Zhigou (TE 6) and Zusanli (ST 36) achieves the good clinical efficacy on adhesive ileus. This therapy can remarkably improve abdominal pain and distention and promote the intestinal peristalsis for the patients and is superior to EA at non-acupoint.</p>
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Acupuncture Analgesia , Acupuncture Points , Electroacupuncture , Ileus , Therapeutics , Pain Management , Tissue Adhesions , TherapeuticsABSTRACT
Objective: The purpose of this study was to evaluate the safety and effectiveness of fast track surgery in laparoscopic gastrectomy for gastric cancer. Methods: All patients received elective gastric cancer resection, and were divided into three groups: group Ⅰ (open gastrecomy, n = 30) , group Ⅱ (open gastrecomy with fast track surgery, n = 30) , and group Ⅲ (laparoscopic gastrecomy with fast track surger-y ,n =30) . Clinical data and gut function were assessed in three groups. Results: There were no significant differences in postoperative complication and the number of lymph node harvest between 3 groups. Blood loss was less in group Ⅲ than group Ⅰ and group Ⅱ (P 0. 05). Conclusion: Postoperative hospital stay can be shorter and recovery of bowel function can be faster in laparoscopic gastrectomy with fast track surgery plan compared to traditional care group. But when using fast track surgery plan, laparoscopic gastrectomy was not superior to open surgery.
ABSTRACT
The aim of this study was to investigate the effect of total parenteral nutrition(TPN), infection, or growth hormone on changes in proliferation of intestinal mucosa epithelial cells and expression of mucosa c jun . Cecal ligation and puncture was used to replicate intra abdominal infection model, and transjugular intracaval catheterization was chosen to give TPN. Experimental rats were divided into four groups: normal control, TPN control, TPN plus sepsis group, and TPN plus growth hormone group. Changes in mucosa thickness, villus height, crypt depth , mucosa c jun mRNA expression and epithelial cell proliferation index were observed. The results showed that all of mucosa thickness, villus height, crypt depth of intestinal mucosa decreased, proliferation of epithelial cells were markedly inhibited in TPN group. Sepsis states aggravated the above changes in intestinal mucosa. Corresponding to mucosa atrophy, expression of c jun reduced obviously. Growth hormone could promote growth of intestinal mucosal cell, improve proliferation of epithelial cells and expression of mucosa c jun. It suggested that changes in c jun expression appeared to be associated with different proliferation states of intestinal mucosa epithelial cells. c jun mRNA could be used as an important marker to reflect mucosa epithelial cell proliferation .